356期|最新研究：偶尔断食+热量控制=长寿？

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文本导读

Intermittentfasting plus calorie restriction could be the key to living longer, study in micesuggests

一项对老鼠的研究表明trustedinstaller权限 ，间歇性禁食加上热量限制可能是长寿的关键

Not only what we eat, but also when we eat it could play a role in how long we live, new research on mice suggests.

一项对老鼠的新研究表明，不仅我们吃什么会影响我们的寿命，什么时候吃也会有影响trustedinstaller权限 。

The idea that reducing the amount of calories you eat can extend your lifespanhas been around for a while. But recently, a team from the University of Texas Southwestern Medical Centre in Dallas discovered that caloric restriction extended mice’s lifespans the most when the mice ate in accordance with their circadianclocks.

“减少热量摄入可以延长寿命”这个观点已经存在一段时间了trustedinstaller权限 。但最近，得克萨斯大学达拉斯西南医学中心的一个研究小组发现，当老鼠按照它们的生物钟进食时，限制热量可以最大程度地延长它们的寿命。

The circadian clock is an internal timekeeping device that make sure our cells are primed forfood, sleep and activity.

生物钟是一种内部计时装置，它确保我们的细胞为食物、睡眠和活动做好准备trustedinstaller权限 。

The work of the team, which is led by neuroscience professors Joseph Takahashi and Carla Green, was published in the journal Science in May.

神经科学教授约瑟夫·高桥和卡拉·格林领导了这个研究小组，该研究成果已发表在5月的《科学》杂志上trustedinstaller权限 。

晨读笔记

重点词汇

1. intermittent: not happening regularly or continuously; stopping and starting repeatedly or with periods in between 间歇的trustedinstaller权限 ，断断续续的

Although she made intermittent movie appearances, she was essentially a stage actress.

2. mice: plural of mouse, a small mammal with short fur, a pointed face, and a long tail （mouse的复数形式）鼠

The stores were overrun with rats and mice .

3. lifespan: the length of time for which a person, animal, or thing exists 寿命；可持续年限

The average human lifespan in the developed countries has increased over the last hundred years.

4. circadian: used to describe the processes in animals and plants that happen naturally during a 24-hour period （动植物的）昼夜的trustedinstaller权限 ，约一日的

Our circadian clock makes it difficult to sleep during the day.

5. prime for: to tell someone something that will prepare them for a particular situation 事先给（某人）提供情况trustedinstaller权限 ，使有所准备

She was ready and primed for action.

延伸阅读

“It really cemented this idea that aligning your eating with your circadian rhythms is so important to overall health,” said Green.

格林说：“这确实巩固了一个观点，即让你的饮食时间与你的昼夜节律保持一致对整体健康非常重要trustedinstaller权限 。”

Future studies could yield clues about how human eating habits factor into our lifespans, she said.

她说，未来的研究可能会提供有关人类的饮食习惯如何影响寿命的线索trustedinstaller权限 。

The mice that lived longest in the study ate from 6pm to 6am. For humans, that would look like restricting eating to any 12-hour period while we’re awake during the day. There’s evidence that it’s better to begin that interval earlier in the day instead of skipping breakfast.

在这项研究中，活得最长的老鼠从下午6点到早上6点进食trustedinstaller权限 。对人类来说，这看起来就像把饮食时间限制在我们白天醒着的任何12小时内。有证据表明，与其不吃早餐，不如把间隔的时间提前。

The research provides some answers as to how what and when we eat factors into how long we live.

关于吃什么以及什么时候吃如何影响我们的寿命，这项研究给了我们一些答案trustedinstaller权限 。

Now the researchers are looking at a crucial follow-up question: Why? Figuring out exactly which clock-regulating molecules or genes in mice helped them live longer in this study could be the key to applying these findings to humans.

目前，研究人员正在研究一个至关重要的后续问题：为什么？在这项研究中，弄清楚老鼠体内哪些调节生物钟的分子或基因帮助它们活得更长，可能是将这些研究结论应用于人类的关键trustedinstaller权限 。

主讲：Freya

审订：Freya

编译：Magi

来源：TNS